Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733826
Species: Homo sapiens
RGD Object: Gene
Symbol: DCXR
Name: dicarbonyl and L-xylulose reductase
Acc ID: CHEBI:37454
Term: 9,10-phenanthroquinone
Definition: A phenanthrene that has formula C14H8O2.
Chemical ID: MESH:C005399
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DCXRincreases metabolic processingEXP 6480464CTDDCXR protein results in increased metabolism of 9,10-phenanthrenequinonePMID:28595002
DCXRmultiple interactionsEXP 6480464CTD9,10-phenanthrenequinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; [CBR2 protein co-treated with NADP] results in increased reduction of and affects the activity of 9,10-phenanthrenequinone; [DCXR protein results in increased metabolism of 9,10-phenanthrenequinone] which results in increased chemical synthesis of Hydroxyl RadicalPMID:21910479 PMID:28595002
Go Back to source page   Continue to Ontology report