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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736765
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP1B1
Name: cytochrome P450 family 1 subfamily B member 1
Acc ID: CHEBI:3719
Term: cirsiliol
Definition: A dimethoxyflavone that is flavone substituted by methoxy groups at positions 6 and 7 and hydroxy groups at positions 5, 3' and 4' respectively.
Chemical ID: MESH:C039824
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP1B1decreases activityEXP 6480464CTDcirsiliol results in decreased activity of CYP1B1 proteinPMID:21482471
CYP1B1increases expressionEXP 6480464CTDcirsiliol results in increased expression of CYP1B1 mRNAPMID:19601638
CYP1B1increases metabolic processingEXP 6480464CTDCYP1B1 protein results in increased metabolism of cirsiliolPMID:19601638
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