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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:37187
Term: lead nitrate
Definition: A lead coordination entity that has formula N2O6Pb.
Chemical ID: MESH:C017461
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionISOBax (Mus musculus)6480464CTDlead nitrate results in increased expression of BAX proteinPMID:23451106
Baxmultiple interactionsISOBax (Mus musculus)6480464CTDmangiferin inhibits the reaction [lead nitrate results in increased expression of BAX protein]PMID:23451106
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTD[lead nitrate results in increased abundance of Lead] which results in increased expression of BAX mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of BAX mRNA]; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of BAX mRNA]PMID:30738203
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