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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3660
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Selenop
Name: selenoprotein P
Acc ID: CHEBI:36904
Term: elemental selenium
Definition: null
Chemical ID: MESH:D012643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Selenopaffects expressionEXP 6480464CTDSelenium affects the expression of SELENOP proteinPMID:19351701
Selenopdecreases expressionEXP 6480464CTDSelenium deficiency results in decreased expression of SELENOP mRNAPMID:19234057
Selenopaffects abundanceISOSelenop (Mus musculus)6480464CTDSELENOP protein affects the abundance of SeleniumPMID:12521380 PMID:12574155 PMID:17014962 PMID:17314095
Selenopaffects expressionISOSelenop (Mus musculus)6480464CTDSelenium affects the expression of SELENOP proteinPMID:17709542
Selenopaffects response to substanceISOSELENOP (Homo sapiens)6480464CTDSELENOP gene SNP affects the susceptibility to SeleniumPMID:19074884
Selenopaffects response to substanceISOSelenop (Mus musculus)6480464CTDSELENOP protein affects the susceptibility to SeleniumPMID:18172410
Selenopdecreases expressionISOSELENOP (Homo sapiens)6480464CTDSelenium results in decreased expression of SELENOP mRNAPMID:19244175
Selenopincreases transportISOSelenop (Mus musculus)6480464CTDSELENOP protein results in increased transport of SeleniumPMID:17961124
Selenopmultiple interactionsISOSELENOP (Homo sapiens)6480464CTD[Mercury results in increased expression of SELENOP protein] which results in increased abundance of Selenium; SELENOP gene SNP affects the reaction [SOD2 gene SNP affects the susceptibility to Selenium]; TUBA4A mutant form results in increased abundance of [Selenium binds to SELENOP protein]PMID:19074884 PMID:27989593 PMID:28478440
Selenopmultiple interactionsISOSelenop (Mus musculus)6480464CTDSELENOP protein affects the transport of and affects the abundance of SeleniumPMID:15638810 PMID:23038251
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