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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:36904
Term: elemental selenium
Definition: null
Chemical ID: MESH:D012643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxmultiple interactionsEXP 6480464CTDSelenium inhibits the reaction [arsenite results in increased expression of BAX protein]PMID:29324385
Baxdecreases expressionISOBax (Mus musculus)6480464CTDSelenium results in decreased expression of BAX proteinPMID:17997286
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTD[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Selenium analog inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of BAX mRNA]PMID:16307838 PMID:27920530
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