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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733100
Species: Homo sapiens
RGD Object: Gene
Symbol: BCL2
Name: BCL2 apoptosis regulator
Acc ID: CHEBI:36728
Term: 20-hydroxypregn-4-en-3-one
Definition: A C21-steroid that is pregnane which contains a double bond between positions 4 and 5 and is substituted by an oxo group at position 3 and a hydroxy group at position 20.
Chemical ID: MESH:C052610
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BCL2decreases expressionEXP 6480464CTD3-hydroxypregn-4-en-20-one results in decreased expression of BCL2 mRNAPMID:19931389
BCL2multiple interactionsEXP 6480464CTD3-hydroxypregn-4-en-20-one inhibits the reaction [5-alpha-Dihydroprogesterone results in increased expression of BCL2 mRNA]PMID:19931389
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