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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69051
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfb1
Name: transforming growth factor, beta 1
Acc ID: CHEBI:36560
Term: zinc oxide
Definition: A zinc molecular entity that has formula OZn.
Chemical ID: MESH:D015034
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfb1decreases expressionISOTgfb1 (Mus musculus)6480464CTDZinc Oxide analog results in decreased expression of TGFB1 mRNAPMID:36100149
Tgfb1increases expressionISOTgfb1 (Mus musculus)6480464CTDZinc Oxide analog results in increased expression of TGFB1 mRNAPMID:35247504
Tgfb1multiple interactionsISOTgfb1 (Mus musculus)6480464CTD1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole inhibits the reaction [Zinc Oxide analog results in increased expression of TGFB1 mRNA]; NFE2L2 protein inhibits the reaction [Zinc Oxide analog results in decreased expression of TGFB1 mRNA]PMID:35247504 PMID:36100149
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