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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619800
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfc
Name: vascular endothelial growth factor C
Acc ID: CHEBI:3654
Term: chlorthalidone
Definition: An isoindole that has formula C14H11ClN2O4S.
Chemical ID: MESH:D002752
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfcdecreases expressionEXP 6480464CTDChlorthalidone results in decreased expression of VEGFC mRNA, Chlorthalidone results in decreased expression of VEGFC protein

PMID:20625077
Vegfcincreases expressionEXP 6480464CTDChlorthalidone results in increased expression of VEGFC protein

PMID:20625077
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.