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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2750
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grpr
Name: gastrin releasing peptide receptor
Acc ID: CHEBI:36386
Term: dichloroacetic acid
Definition: An organochlorine compound comprising acetic acid carrying two chloro substituents at the 2-position. It occurs in nature in seaweed, Asparagopsis taxiformis.
Chemical ID: MESH:D003999
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases response to substanceISORGD:7319596480464CTDGRPR mutant form results in increased susceptibility to Dichloroacetic Acid

PMID:25630799
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.