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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1315044
Species: Mus musculus
RGD Object: Gene
Symbol: Map3k5
Name: mitogen-activated protein kinase kinase kinase 5
Acc ID: CHEBI:36274
Term: glycochenodeoxycholic acid
Definition: A bile acid glycine conjugate having 3alpha,7alpha-dihydroxy-5beta-cholan-24-oyl as the bile acid component.
Chemical ID: MESH:D005999
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map3k5multiple interactionsISOMAP3K5 (Homo sapiens)6480464CTD[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of MAP3K5 mRNA; [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of MAP3K5 mRNAPMID:33819548
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