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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619930
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb11
Name: ATP binding cassette subfamily B member 11
Acc ID: CHEBI:36259
Term: taurolithocholic acid
Definition: The bile acid taurine conjugate of lithocholic acid.
Chemical ID: MESH:D013658
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb11affects localizationEXP 6480464CTDTaurolithocholic Acid affects the localization of ABCB11 proteinPMID:12865277
Abcb11multiple interactionsEXP 6480464CTDTaurolithocholic Acid affects the localization of and affects the activity of ABCB11 proteinPMID:15763547
Abcb11decreases activityISOABCB11 (Homo sapiens)6480464CTDTaurolithocholic Acid results in decreased activity of ABCB11 proteinPMID:24014644
Abcb11multiple interactionsISOABCB11 (Homo sapiens)6480464CTDTaurolithocholic Acid inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]PMID:24014644
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