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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344608
Species: Homo sapiens
RGD Object: Gene
Symbol: PRKACA
Name: protein kinase cAMP-activated catalytic subunit alpha
Acc ID: CHEBI:36259
Term: taurolithocholic acid
Definition: The bile acid taurine conjugate of lithocholic acid.
Chemical ID: MESH:D013658
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRKACAincreases activityISOPrkaca (Rattus norvegicus)6480464CTDTaurolithocholic Acid results in increased activity of PRKACA proteinPMID:31300867
PRKACAmultiple interactionsISOPrkaca (Rattus norvegicus)6480464CTDJTE 013 inhibits the reaction [Taurolithocholic Acid results in increased activity of PRKACA protein]; KT 5720 inhibits the reaction [Taurolithocholic Acid results in increased activity of PRKACA protein]; RMI 12330A inhibits the reaction [Taurolithocholic Acid results in increased activity of PRKACA protein]PMID:31300867
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