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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316258
Species: Homo sapiens
RGD Object: Gene
Symbol: EPHA2
Name: EPH receptor A2
Acc ID: CHEBI:36237
Term: cholanic acid
Definition: A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24.
Chemical ID: MESH:C007036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EPHA2multiple interactionsEXP 6480464CTDcholanic acid binds to and results in decreased activity of EPHA2 protein; cholanic acid inhibits the reaction [EFNA1 protein binds to and results in increased phosphorylation of and results in increased activity of EPHA2 protein]PMID:22529030
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