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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10127
Species: Mus musculus
RGD Object: Gene
Symbol: Ahr
Name: aryl-hydrocarbon receptor
Acc ID: CHEBI:35860
Term: 1-methylphenanthrene
Definition: A member of the class of phenanthrenes that is phenanthrene substituted by a methyl group at position 1.
Chemical ID: MESH:C041507
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ahrincreases activityISOAhr (Rattus norvegicus)6480464CTD1-methylphenanthrene results in increased activity of AHR proteinPMID:11339718 PMID:17941746
Ahrmultiple interactionsISOAhr (Rattus norvegicus)6480464CTD[1-methylphenanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNAPMID:17941746
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