Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1308314
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Nlrp3
Name:	NLR family, pyrin domain containing 3

Acc ID:	CHEBI:35842
Term:	antirheumatic drug
Definition:	A drug used to treat rheumatoid arthritis.
Chemical ID:	MESH:D018501

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Nlrp3	decreases expression	ISO	NLRP3 (Homo sapiens)	6480464	CTD	Antirheumatic Agents results in decreased expression of NLRP3 mRNA	PMID:24449571

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.