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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621392
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccn2
Name: cellular communication network factor 2
Acc ID: CHEBI:35828
Term: arsenic(3+)
Definition: A monoatomic arsenic that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDArsenic results in increased expression of CCN2 mRNA

PMID:24348802
multiple interactionsEXP 6480464CTDGrape Seed Extract inhibits the reaction [Arsenic results in increased expression of CCN2 mRNA]

PMID:24348802
affects expressionISORGD:7310136480464CTDArsenic affects the expression of CCN2 protein

PMID:24675094
increases expressionISORGD:7310146480464CTDArsenic results in increased expression of CCN2 mRNA

PMID:23942117
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.