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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620089
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ocln
Name: occludin
Acc ID: CHEBI:35828
Term: arsenic(3+)
Definition: A monoatomic arsenic that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDArsenic results in decreased expression of OCLN mRNA

PMID:28829631
affects localizationISORGD:16240786480464CTDArsenic affects the localization of OCLN protein

PMID:24349408
affects methylationISORGD:7329856480464CTDArsenic affects the methylation of OCLN gene

PMID:25304211
increases expressionISORGD:7329856480464CTDArsenic results in increased expression of OCLN protein

PMID:24349408
multiple interactionsISORGD:7329856480464CTDArsenic affects the phosphorylation of and results in increased expression of OCLN protein

PMID:24349408
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.