Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	69124
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Lep
Name:	leptin

Acc ID:	CHEBI:35817
Term:	roxarsone
Definition:	An organoarsonic acid where the organyl group is 4-hydroxy-3-nitrophenyl.
Chemical ID:	MESH:D012406

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Lep	decreases expression	ISO	LEP (Homo sapiens)	6480464	CTD	Roxarsone results in decreased expression of LEP mRNA	PMID:18414637

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.