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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730818
Species: Mus musculus
RGD Object: Gene
Symbol: Adora1
Name: adenosine A1 receptor
Acc ID: CHEBI:35696
Term: cobalt dichloride
Definition: A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants.
Chemical ID: MESH:C018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adora1decreases response to substanceEXP 6480464CTDADORA1 protein results in decreased susceptibility to cobaltous chloridePMID:18727925
Adora1multiple interactionsEXP 6480464CTD[1,3-dipropyl-8-cyclopentylxanthine binds to and results in decreased activity of ADORA1 protein] which results in increased susceptibility to cobaltous chloridePMID:18727925
Adora1decreases expressionISOAdora1 (Rattus norvegicus)6480464CTDcobaltous chloride results in decreased expression of ADORA1 mRNAPMID:24386269
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