GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pld1 | decreases expression | ISO | Pld1 (Rattus norvegicus) | 6480464 | CTD | cobaltous chloride results in decreased expression of PLD1 mRNA | PMID:24386269 | Pld1 | increases activity | ISO | PLD1 (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in increased activity of PLD1 protein | PMID:17640750 | Pld1 | multiple interactions | ISO | PLD1 (Homo sapiens) | 6480464 | CTD | 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]]; Acetylcysteine inhibits the reaction [PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]]; PLD1 protein promotes the reaction [cobaltous chloride results in increased abundance of Dinoprostone]; PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]; Reactive Oxygen Species affects the reaction [PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]]; rottlerin inhibits the reaction [PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]] | PMID:17640750 | | ||||||||||||||||||||||
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