GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ddit4 | increases expression | EXP | | 6480464 | CTD | cobaltous chloride results in increased expression of DDIT4 mRNA; cobaltous chloride results in increased expression of DDIT4 protein | PMID:22689575 PMID:24386269 | Ddit4 | multiple interactions | EXP | | 6480464 | CTD | [cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 mRNA; [cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 protein; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 mRNA]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 protein] | PMID:24989011 | Ddit4 | increases expression | ISO | DDIT4 (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in increased expression of DDIT4 mRNA; cobaltous chloride results in increased expression of DDIT4 protein | PMID:17307335 PMID:19376846 PMID:24356939 | Ddit4 | multiple interactions | ISO | DDIT4 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of DDIT4 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of DDIT4 protein]; [Plicamycin results in decreased activity of SP1 protein] inhibits the reaction [cobaltous chloride results in increased expression of DDIT4 mRNA]; [Plicamycin results in decreased activity of SP1 protein] inhibits the reaction [cobaltous chloride results in increased expression of DDIT4 protein]; HIF1A protein affects the reaction [cobaltous chloride results in increased expression of DDIT4 mRNA]; HIF1A protein promotes the reaction [SP1 protein promotes the reaction [cobaltous chloride results in increased expression of DDIT4]]; SP1 protein promotes the reaction [cobaltous chloride results in increased expression of DDIT4 mRNA] | PMID:17307335 | | ||||||||||||||||||||||
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