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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: G6pd
Name: glucose-6-phosphate dehydrogenase
Acc ID: CHEBI:35696
Term: cobalt dichloride
Definition: A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants.
Chemical ID: MESH:C018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6pdincreases activityEXP 6480464CTDcobaltous chloride results in increased activity of G6PD proteinPMID:15225644
G6pdincreases expressionEXP 6480464CTDcobaltous chloride results in increased expression of G6PD mRNAPMID:15225644
G6pddecreases expressionISOG6PD (Homo sapiens)6480464CTDcobaltous chloride results in decreased expression of G6PD mRNAPMID:19376846
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