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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308528
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Efemp1
Name: EGF containing fibulin extracellular matrix protein 1
Acc ID: CHEBI:35696
Term: cobalt dichloride
Definition: A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants.
Chemical ID: MESH:C018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13183516480464CTDcobaltous chloride results in decreased expression of EFEMP1 mRNA

PMID:19320972, PMID:19376846
decreases secretionISORGD:13183516480464CTDcobaltous chloride results in decreased secretion of EFEMP1 protein

PMID:22079246
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.