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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737482
Species: Homo sapiens
RGD Object: Gene
Symbol: BIRC5
Name: baculoviral IAP repeat containing 5
Acc ID: CHEBI:35591
Term: pregnenolone 16alpha-carbonitrile
Definition: An aliphatic nitrile that has formula C22H31NO2.
Chemical ID: MESH:D011285
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BIRC5increases expressionISOBirc5 (Rattus norvegicus)6480464CTDPregnenolone Carbonitrile results in increased expression of BIRC5 mRNAPMID:30047161
BIRC5increases expressionISOBirc5 (Mus musculus)6480464CTDPregnenolone Carbonitrile results in increased expression of BIRC5 mRNAPMID:22698814 PMID:28903501
BIRC5multiple interactionsISOBirc5 (Mus musculus)6480464CTD[Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of BIRC5 mRNAPMID:33398415
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