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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735261
Species: Mus musculus
RGD Object: Gene
Symbol: Ces1d
Name: carboxylesterase 1D
Acc ID: CHEBI:35591
Term: pregnenolone 16alpha-carbonitrile
Definition: An aliphatic nitrile that has formula C22H31NO2.
Chemical ID: MESH:D011285
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ces1dincreases expressionEXP 6480464CTDPregnenolone Carbonitrile results in increased expression of CES1D mRNA; Pregnenolone Carbonitrile results in increased expression of CES1D proteinPMID:20359477 PMID:26179144 PMID:28903501
Ces1dmultiple interactionsEXP 6480464CTDPregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CES1D mRNA]PMID:20359477
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