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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730835
Species: Mus musculus
RGD Object: Gene
Symbol: Akr1b7
Name: aldo-keto reductase family 1, member B7
Acc ID: CHEBI:35559
Term: furan
Definition: A monocyclic heteroarene with a structure consisting of a 5-membered ring containing four carbons and one oxygen, with formula C4H4O. It is a toxic, flammable, low-boiling (31degreeC) colourless liquid.
Chemical ID: MESH:C039281
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1b7increases expressionISORGD:6202576480464CTDfuran results in increased expression of AKR1B7 mRNA

PMID:25539665, PMID:26194646
Akr1b7increases methylationISORGD:6202576480464CTDfuran results in increased methylation of AKR1B7 gene

PMID:22079235
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.