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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2503
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nqo1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:35559
Term: furan
Definition: A monocyclic heteroarene with a structure consisting of a 5-membered ring containing four carbons and one oxygen, with formula C4H4O. It is a toxic, flammable, low-boiling (31degreeC) colourless liquid.
Chemical ID: MESH:C039281
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nqo1increases expressionEXP 6480464CTDfuran results in increased expression of NQO1 mRNAPMID:15120968 PMID:25539665 PMID:26194646
Nqo1increases methylationEXP 6480464CTDfuran results in increased methylation of NQO1 genePMID:22079235
Nqo1increases expressionISONqo1 (Mus musculus)6480464CTDfuran results in increased expression of NQO1 mRNAPMID:24183702 PMID:24910943 PMID:37517673
Nqo1multiple interactionsISONqo1 (Mus musculus)6480464CTD[Bromodeoxyuridine co-treated with furan] results in increased expression of NQO1 mRNAPMID:24910943
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