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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550230
Species: Mus musculus
RGD Object: Gene
Symbol: Tnfrsf12a
Name: tumor necrosis factor receptor superfamily, member 12a
Acc ID: CHEBI:35559
Term: furan
Definition: A monocyclic heteroarene with a structure consisting of a 5-membered ring containing four carbons and one oxygen, with formula C4H4O. It is a toxic, flammable, low-boiling (31degreeC) colourless liquid.
Chemical ID: MESH:C039281
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf12aincreases expressionEXP 6480464CTDfuran results in increased expression of TNFRSF12A mRNAPMID:24183702 PMID:24910943 PMID:37517673
Tnfrsf12amultiple interactionsEXP 6480464CTD[Bromodeoxyuridine co-treated with furan] results in increased expression of TNFRSF12A mRNAPMID:24910943
Tnfrsf12aincreases methylationISOTnfrsf12a (Rattus norvegicus)6480464CTDfuran results in increased methylation of TNFRSF12A genePMID:22079235
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