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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352582
Species: Homo sapiens
RGD Object: Gene
Symbol: IL6
Name: interleukin 6
Acc ID: CHEBI:35559
Term: furan
Definition: A monocyclic heteroarene with a structure consisting of a 5-membered ring containing four carbons and one oxygen, with formula C4H4O. It is a toxic, flammable, low-boiling (31degreeC) colourless liquid.
Chemical ID: MESH:C039281
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL6increases expressionISOIl6 (Mus musculus)6480464CTDfuran results in increased expression of IL6 mRNAPMID:34450210
IL6increases expressionISOIl6 (Rattus norvegicus)6480464CTDfuran results in increased expression of IL6 mRNAPMID:27387713
IL6multiple interactionsISOIl6 (Mus musculus)6480464CTDrhodioloside inhibits the reaction [furan results in increased expression of IL6 mRNA]PMID:34450210
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