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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731555
Species: Mus musculus
RGD Object: Gene
Symbol: Gck
Name: glucokinase
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gckaffects expressionEXP 6480464CTDperfluorooctanoic acid affects the expression of GCK mRNAPMID:19429403
Gckdecreases expressionEXP 6480464CTDperfluorooctanoic acid results in decreased expression of GCK mRNAPMID:23626681
Gckincreases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of GCK proteinPMID:28947262
Gckmultiple interactionsEXP 6480464CTDDietary Fats, Unsaturated promotes the reaction [perfluorooctanoic acid results in increased expression of GCK mRNA]PMID:23626681
Gckdecreases expressionISOGck (Rattus norvegicus)6480464CTDperfluorooctanoic acid results in decreased expression of GCK mRNAPMID:19162173
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