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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730835
Species: Mus musculus
RGD Object: Gene
Symbol: Akr1b7
Name: aldo-keto reductase family 1, member B7
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1b7increases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of AKR1B7 mRNA

PMID:18281256, PMID:27153767
Akr1b7multiple interactionsEXP 6480464CTDPPARA protein affects the reaction [perfluorooctanoic acid results in increased expression of AKR1B7 mRNA]

PMID:18281256
Akr1b7increases expressionISORGD:6202576480464CTDperfluorooctanoic acid results in increased expression of AKR1B7 mRNA

PMID:28511854
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.