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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708482
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dhrs4
Name: dehydrogenase/reductase 4
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:7321506480464CTDperfluorooctanoic acid affects the expression of DHRS4 mRNA

PMID:18281256
increases expressionISORGD:7321506480464CTDperfluorooctanoic acid results in increased expression of DHRS4 mRNA

PMID:17681415, PMID:28558994
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.