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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69402
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acsl5
Name: acyl-CoA synthetase long-chain family member 5
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acsl5decreases expressionEXP 6480464CTDperfluorooctanoic acid results in decreased expression of ACSL5 mRNAPMID:19162173
Acsl5affects expressionISOAcsl5 (Mus musculus)6480464CTDperfluorooctanoic acid affects the expression of ACSL5 mRNAPMID:19429403
Acsl5increases expressionISOAcsl5 (Mus musculus)6480464CTDperfluorooctanoic acid results in increased expression of ACSL5 mRNAPMID:17681415 PMID:18467677 PMID:20936131 PMID:30657992 PMID:34252412
Acsl5multiple interactionsISOAcsl5 (Mus musculus)6480464CTDPPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of ACSL5 mRNA]PMID:18467677 PMID:20936131
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