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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619849
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hacl1
Name: 2-hydroxyacyl-CoA lyase 1
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hacl1increases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of HACL1 mRNA; perfluorooctanoic acid results in increased expression of HACL1 proteinPMID:16221955 PMID:28511854 PMID:34958885
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