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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61879
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Psmb5
Name: proteasome 20S subunit beta 5
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Psmb5increases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of PSMB5 mRNA; perfluorooctanoic acid results in increased expression of PSMB5 proteinPMID:19162173 PMID:21318169 PMID:34958885
Psmb5affects expressionISOPsmb5 (Mus musculus)6480464CTDperfluorooctanoic acid affects the expression of PSMB5 mRNAPMID:19429403
Psmb5increases expressionISOPsmb5 (Mus musculus)6480464CTDperfluorooctanoic acid results in increased expression of PSMB5 mRNAPMID:18467677
Psmb5multiple interactionsISOPsmb5 (Mus musculus)6480464CTDPPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of PSMB5 mRNA]PMID:18467677
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