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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2794
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hgf
Name: hepatocyte growth factor
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hgfdecreases expressionISOHgf (Mus musculus)6480464CTDperfluorooctanoic acid results in decreased expression of HGF proteinPMID:22414604
Hgfdecreases expressionISOHGF (Homo sapiens)6480464CTDperfluorooctanoic acid results in decreased expression of HGF mRNA; perfluorooctanoic acid results in decreased expression of HGF proteinPMID:32916415 PMID:37302725
Hgfincreases expressionISOHgf (Mus musculus)6480464CTDperfluorooctanoic acid results in increased expression of HGF proteinPMID:20118188
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