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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2239
Species: Rattus norvegicus
RGD Object: Gene
Symbol: C8b
Name: complement C8 beta chain
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
C8bdecreases expressionEXP 6480464CTDperfluorooctanoic acid results in decreased expression of C8B mRNAPMID:19162173
C8baffects expressionISOC8b (Mus musculus)6480464CTDperfluorooctanoic acid affects the expression of C8B mRNAPMID:19429403
C8bdecreases expressionISOC8b (Mus musculus)6480464CTDperfluorooctanoic acid results in decreased expression of C8B mRNAPMID:18467677 PMID:20936131 PMID:30711707
C8bmultiple interactionsISOC8b (Mus musculus)6480464CTDPPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of C8B mRNA]PMID:18467677
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