GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | EXP | | 6480464 | CTD | perfluorooctanoic acid results in increased expression of BAX mRNA | PMID:19162173 PMID:21318169 | Bax | affects expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | perfluorooctanoic acid affects the expression of BAX mRNA | PMID:32068100 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | perfluorooctanoic acid results in increased expression of BAX mRNA; perfluorooctanoic acid results in increased expression of BAX protein | PMID:28219760 PMID:35066053 PMID:37044272 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | perfluorooctanoic acid results in increased expression of BAX mRNA; perfluorooctanoic acid results in increased expression of BAX protein | PMID:32790152 PMID:32971237 PMID:34765786 PMID:35123991 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [perfluorooctanoic acid co-treated with Carbenoxolone] results in increased expression of BAX protein; Tretinoin inhibits the reaction [perfluorooctanoic acid results in increased expression of BAX protein] | PMID:32971237 | |
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