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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1620647
Species: Mus musculus
RGD Object: Gene
Symbol: Acot8
Name: acyl-CoA thioesterase 8
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acot8increases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of ACOT8 mRNAPMID:17681415 PMID:23626681
Acot8multiple interactionsEXP 6480464CTDDietary Fats, Unsaturated promotes the reaction [perfluorooctanoic acid results in increased expression of ACOT8 mRNA]PMID:23626681
Acot8increases expressionISOAcot8 (Rattus norvegicus)6480464CTDperfluorooctanoic acid results in increased expression of ACOT8 mRNA; perfluorooctanoic acid results in increased expression of ACOT8 proteinPMID:16221955 PMID:34958885
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