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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347922
Species: Homo sapiens
RGD Object: Gene
Symbol: PCK1
Name: phosphoenolpyruvate carboxykinase 1
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PCK1increases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of PCK1 mRNAPMID:21723365 PMID:27153767 PMID:32588087
PCK1decreases expressionISOPck1 (Rattus norvegicus)6480464CTDperfluorooctanoic acid results in decreased expression of PCK1 proteinPMID:34958885
PCK1increases expressionISOPck1 (Rattus norvegicus)6480464CTDperfluorooctanoic acid results in increased expression of PCK1 mRNAPMID:28511854
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