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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317785
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c65
Name: cytochrome P450, family 2, subfamily c, polypeptide 65
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c65affects expressionEXP 6480464CTDperfluorooctanoic acid affects the expression of CYP2C65 mRNAPMID:18281256
Cyp2c65increases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of CYP2C65 mRNAPMID:20936131 PMID:28558994
Cyp2c65multiple interactionsEXP 6480464CTDPPARA protein inhibits the reaction [perfluorooctanoic acid results in increased expression of CYP2C65 mRNA]PMID:20936131
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