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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310993
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tet1
Name: tet methylcytosine dioxygenase 1
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tet1decreases expressionISOTET1 (Homo sapiens)6480464CTDperfluorooctanoic acid results in decreased expression of TET1 mRNAPMID:32068100
Tet1increases expressionISOTet1 (Mus musculus)6480464CTDperfluorooctanoic acid results in increased expression of TET1 mRNAPMID:32320774
Tet1multiple interactionsISOTET1 (Homo sapiens)6480464CTD[bisphenol S co-treated with perfluorooctanoic acid] results in increased expression of TET1 mRNAPMID:37834465
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