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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735413
Species: Homo sapiens
RGD Object: Gene
Symbol: STAR
Name: steroidogenic acute regulatory protein
Acc ID: CHEBI:35459
Term: diisononyl phthalate
Definition: The diisononyl ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:C012125
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
STARmultiple interactionsEXP 6480464CTD[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of STAR mRNA]PMID:37552060
STARdecreases expressionISOStar (Rattus norvegicus)6480464CTDdiisononyl phthalate results in decreased expression of STAR mRNAPMID:21633115 PMID:22112501 PMID:25445723 PMID:33983380
STARmultiple interactionsISOStar (Mus musculus)6480464CTD[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate] results in increased expression of STAR mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of STAR mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of STAR mRNA; [Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate] results in decreased expression of STAR mRNAPMID:28013214 PMID:30802670 PMID:34597818 PMID:37839492
STARmultiple interactionsISOStar (Rattus norvegicus)6480464CTD[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of STAR mRNA; [diisobutyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate] results in decreased expression of STAR mRNAPMID:35762964 PMID:37788136
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