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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318374
Species: Homo sapiens
RGD Object: Gene
Symbol: SIRT1
Name: sirtuin 1
Acc ID: CHEBI:35459
Term: diisononyl phthalate
Definition: The diisononyl ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:C012125
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SIRT1decreases expressionEXP 6480464CTDdiisononyl phthalate results in decreased expression of SIRT1 mRNA; diisononyl phthalate results in decreased expression of SIRT1 proteinPMID:31423773
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