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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735541
Species: Homo sapiens
RGD Object: Gene
Symbol: BAD
Name: BCL2 associated agonist of cell death
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BADdecreases expressionEXP 6480464CTDCadmium Chloride results in decreased expression of BAD mRNAPMID:19426795
BADincreases expressionEXP 6480464CTDCadmium Chloride results in increased expression of BAD mRNA; Cadmium Chloride results in increased expression of BAD proteinPMID:24291162 PMID:33129824
BADdecreases expressionISOBad (Rattus norvegicus)6480464CTDCadmium Chloride results in decreased expression of BAD mRNAPMID:33453195
BADdecreases phosphorylationISOBad (Mus musculus)6480464CTDCadmium Chloride results in decreased phosphorylation of BAD proteinPMID:34998821
BADincreases expressionISOBad (Rattus norvegicus)6480464CTDCadmium Chloride results in increased expression of BAD proteinPMID:23717155
BADincreases expressionISOBad (Mus musculus)6480464CTDCadmium Chloride results in increased expression of BAD proteinPMID:21420465
BADmultiple interactionsISOBad (Rattus norvegicus)6480464CTDPlant Extracts inhibits the reaction [Cadmium Chloride results in increased expression of BAD protein]PMID:23717155
BADmultiple interactionsISOBad (Mus musculus)6480464CTDarjunolic acid inhibits the reaction [Cadmium Chloride results in increased expression of BAD protein]PMID:21420465
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