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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730985
Species: Mus musculus
RGD Object: Gene
Symbol: Col1a2
Name: collagen, type I, alpha 2
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col1a2decreases expressionEXP 6480464CTDCadmium Chloride results in decreased expression of COL1A2 mRNAPMID:24982889
Col1a2multiple interactionsEXP 6480464CTD[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with Dietary Fats] results in increased expression of COL1A2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of COL1A2 mRNA; [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL1A2 mRNAPMID:19840844 PMID:30912652 PMID:37325564
Col1a2increases expressionISOCol1a2 (Rattus norvegicus)6480464CTDCadmium Chloride results in increased expression of COL1A2 mRNAPMID:25993096
Col1a2multiple interactionsISOCOL1A2 (Homo sapiens)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of COL1A2 mRNAPMID:29741670
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