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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628899
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ripk3
Name: receptor-interacting serine-threonine kinase 3
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ripk3increases expressionEXP 6480464CTDCadmium Chloride results in increased expression of RIPK3 mRNAPMID:25993096
Ripk3increases expressionISORIPK3 (Homo sapiens)6480464CTDCadmium Chloride results in increased expression of RIPK3 proteinPMID:35844137
Ripk3increases expressionISORipk3 (Mus musculus)6480464CTDCadmium Chloride results in increased expression of RIPK3 proteinPMID:35844137
Ripk3multiple interactionsISORIPK3 (Homo sapiens)6480464CTDCaptopril inhibits the reaction [Cadmium Chloride results in increased expression of RIPK3 protein]PMID:35844137
Ripk3multiple interactionsISORipk3 (Mus musculus)6480464CTDMelatonin inhibits the reaction [Cadmium Chloride results in increased expression of RIPK3 protein]PMID:35844137
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