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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3757
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srd5a1
Name: steroid 5 alpha-reductase 1
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDCadmium Chloride results in increased expression of SRD5A1 mRNA, Cadmium Chloride results in increased expression of SRD5A1 protein

PMID:25993096, PMID:29214744
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.