GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Spp1 | increases export | EXP | | 6480464 | CTD | Cadmium Chloride results in increased export of SPP1 protein | PMID:29421648 | Spp1 | increases expression | EXP | | 6480464 | CTD | Cadmium Chloride results in increased expression of SPP1 mRNA; Cadmium Chloride results in increased expression of SPP1 protein | PMID:17327700 PMID:26815315 | Spp1 | increases methylation | EXP | | 6480464 | CTD | Cadmium Chloride results in increased methylation of SPP1 promoter | PMID:22457795 | Spp1 | multiple interactions | EXP | | 6480464 | CTD | Curcumin inhibits the reaction [Cadmium Chloride results in increased export of SPP1 protein] | PMID:29421648 | Spp1 | decreases expression | ISO | SPP1 (Homo sapiens) | 6480464 | CTD | Cadmium Chloride results in decreased expression of SPP1 mRNA | PMID:22019892 | Spp1 | increases expression | ISO | SPP1 (Homo sapiens) | 6480464 | CTD | Cadmium Chloride results in increased expression of SPP1 mRNA | PMID:17547211 | Spp1 | multiple interactions | ISO | Spp1 (Mus musculus) | 6480464 | CTD | [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SPP1 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SPP1 mRNA | PMID:19840844 PMID:31904401 | Spp1 | multiple interactions | ISO | SPP1 (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in decreased expression of SPP1 mRNA]; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SPP1 mRNA | PMID:22019892 PMID:29741670 | |
Go Back to source page | Continue to Ontology report |