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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2944
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Junb
Name: JunB proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Junbincreases expressionEXP 6480464CTDCadmium Chloride results in increased expression of JUNB mRNAPMID:19010381 PMID:25993096
Junbincreases expressionISOJunb (Mus musculus)6480464CTDCadmium Chloride results in increased expression of JUNB mRNAPMID:11171528 PMID:24982889
Junbmultiple interactionsISOJUNB (Homo sapiens)6480464CTD[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of JUNB mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of JUNB mRNA; [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of JUNB mRNAPMID:12634122 PMID:33309878 PMID:36602393
Junbmultiple interactionsISOJunb (Mus musculus)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of JUNB mRNAPMID:37325564
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